Table 2.
Time (week no.) | -2 to 0 | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 17 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Enrollment | ||||||||||||||||
Eligibility screen | X | |||||||||||||||
Informed consent | X | |||||||||||||||
Randomization | X | |||||||||||||||
Intervention | X---------------------------------------------------------------------------------------------------------------------------X | |||||||||||||||
Physical tests and examinations | ||||||||||||||||
30s-CST (primary outcome) | X | X | X | X | ||||||||||||
6MWT | X | X | X | X | ||||||||||||
Handgrip strength | X | X | X | X | ||||||||||||
Gait speed test | X | X | X | X | ||||||||||||
Physical activitya | X | X | ||||||||||||||
DXA | X | X | ||||||||||||||
BI | X | X | ||||||||||||||
Body weighta | X | X | X | X | ||||||||||||
Inflammatory biomarkers | X | X | X | X | ||||||||||||
PROMs | ||||||||||||||||
PRPS | X | X | X | X | ||||||||||||
MDASIa | X | X | X | X | ||||||||||||
EORTC-QLQ-C30 | X | X | X | X | ||||||||||||
HADS | X | X | X | X | ||||||||||||
Qualitative exploration | ||||||||||||||||
Individual Interviews | X | |||||||||||||||
Feasibility | ||||||||||||||||
Adherence | X | X | X | X | X | X | X | X | X | X | X | X | X | X | ||
Attrition | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X |
Adverse events | X | X | X | X | X | X | X | X | X | X | X | X | X | X | ||
Oncological treatment | ||||||||||||||||
Treatment related toxicityb | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X |
Dose-reductionsb | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X |
Hospitalizations | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X |
Survival | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X | X |
aOnce weekly for participants in the intervention group bRegistered for every treatment course
Abbreviations: 30s-CST 30-s chair stand test, 6MWT six-minute-walk-test, BI bioelectrical impedance, DXA whole-body dual-energy x-ray absorptiometry, EORTC-QLQ-C30 European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire C30, HADS Hospital Anxiety and Depression Scale, MDASI M.D. Anderson Symptom Inventory, PRPS patient-reported performance status