Table 3.
Maternal ART-related adverse effects categorized using the DAIDS Toxicity Grading Scale according to periods of delivery
| 2000–2009 (n = 452) | 2010–2015 (n = 347) | p* | |
|---|---|---|---|
| % | % | ||
| Hemoglobin First Trimester | |||
| Grade 1 | 92.5 | 94.6 | 0.516 |
| Grade 2 | 6.4 | 4.8 | |
| Grade 3 | 1.1 | 0.6 | |
| Hemoglobin Third Trimester | |||
| Grade 1 | 83.6 | 84.9 | 0.916 |
| Grade 2 | 15.5 | 14.6 | |
| Grade 3 | 0.9 | 0.5 | |
| AST First Trimester | |||
| Grade 1 | 98.4 | 98.9 | |
| Grade 2 | 0.7 | 0.7 | 1.000 |
| Grade 3 | 0.7 | 0.4 | |
| Grade 4 | 0.3 | 0.0 | |
| AST Third Trimester | |||
| Grade 1 | 99.4 | 100.0 | |
| Grade 2 | 0.6 | 0.0 | 1.000 |
| Grade 3 | 0.0 | 0.0 | |
| Grade 4 | 0.0 | 0.0 | |
| ALT First Trimester | |||
| Grade 1 | 98.7 | 98.9 | |
| Grade 2 | 0.7 | 0.7 | 1.000 |
| Grade 3 | 0.3 | 0.4 | |
| Grade 4 | 0.3 | 0.0 | |
| ALT Third Trimester | |||
| Grade 1 | 99.4 | 99.4 | |
| Grade 2 | 0.6 | 0.6 | 1.000 |
| Grade 3 | 0.0 | 0.0 | |
| Grade 4 | 0.0 | 0.0 | |
| Cholesterol First Trimester | |||
| Grade 1 | 91.1 | 90.6 | 0.631 |
| Grade 2 | 6.9 | 8.4 | |
| Grade 3 | 2.0 | 1.0 | |
| Cholesterol Third Trimester | |||
| Grade 1 | 69.7 | 64.9 | 0.792 |
| Grade 2 | 21.2 | 24.7 | |
| Grade 3 | 9.1 | 10.3 | |
| Triglyceride First Trimester | |||
| Grade 1 | 95.5 | 94.2 | 0.820 |
| Grade 2 | 4.5 | 5.3 | |
| Grade 3 | 0.0 | 0.5 | |
| Grade 4 | 0.0 | 0.0 | |
| Triglyceride Third Trimester | |||
| Grade 1 | 83.3 | 77.1 | 0.514 |
| Grade 2 | 15.6 | 20.8 | |
| Grade 3 | 1.0 | 2.1 | |
| Grade 4 | 0.0 | 0.0 | |
| Platelets First Trimester | |||
| Grade 1 | 98.4 | 97.2 | 0.496 |
| Grade 2 | 1.1 | 2.2 | |
| Grade 3 | 0.0 | 0.3 | |
| Grade 4 | 0.5 | 0.3 | |
| Platelets Third Trimester | |||
| Grade 1 | 99.5 | 98.8 | 0.480 |
| Grade 2 | 0.5 | 0.5 | |
| Grade 3 | 0.0 | 1.0 | |
| Grade 4 | 0.0 | 0.0 | |
| Bilirrubin First Trimester | |||
| Grade 1 | 98.6 | 95.2 | 0.264 |
| Grade 2 | 1.4 | 3.0 | |
| Grade 3 | 0.0 | 1.8 | |
| Grade 4 | 0.0 | 0.0 | |
| Bilirrubin Third Trimester | |||
| Grade 1 | 97.6 | 93.0 | 0.200 |
| Grade 2 | 1.2 | 6.1 | |
| Grade 3 | 1.2 | 0.9 | |
| Grade 4 | 0.0 | 0.0 | |
| Total | 100 | 100 | |
ALT alanine aminotransferase, AST aspartate aminotransferase