Table 2.
Allele and Genotype distribution of the selected SNPs among the cases and the controls
| SNP | Genotype/MAF | Controls (n = 219) | Cases (n = 404) | OR (CI) | p-value |
|---|---|---|---|---|---|
| rs662 (PON1) | AA | 84 | 118 | 1.15 (0.898–1.470) | 0.02 |
| AG | 84 | 175 | |||
| GG | 51 | 111 | |||
| MAF | 0.425 | 0.491 | |||
| rs5918 (ITGB3) | CC | 129 | 190 | 1.179 (0.931–1.477) | 0.05 |
| CT | 64 | 171 | |||
| TT | 26 | 43 | |||
| MAF | 0.256 | 0.318 | |||
| rs671 (ALDH2) | GG | 101 | 168 | 0.993 (0.770–1.28) | 0.421 |
| GA | 93 | 190 | |||
| AA | 25 | 46 | |||
| MAF | 0.326 | 0.349 | |||
| rs1800795 (IL-6) | GG | 96 | 194 | 1.21 (0.943–1.540) | 0.153 |
| GC | 90 | 133 | |||
| CC | 33 | 99 | |||
| MAF | 0.356 | 0.388 |
Legend: Selected SNPs allele/genotype frequencies, MAF Minor Allele Frequency, p-value indicates the significance of difference in genotype frequencies between cases and controls from chi-squared test, Odds ratios are for risk alleles. CI Confidence Interval