Table 3.

Comparison of the effect of genotypes of Singlr SNPs and combined GRS

SNP	Genotype	TC (mg/dL)	TG (mg/dL)	LDL-C (mg/dL)	HDL-C (mg/dL)
rs662 (PON1)	AA	175.51 ± 8.47	184.94 ± 7.17	81.38 ± 3.57	70.08 ± 1.77
	AG	170.61 ± 3.75	187.89 ± 6.26	77.05 ± 2.32	68.54 ± 1.68
	GG	181.25 ± 5.08	196.81 ± 13.8	76.45 ± 1.99	65.54 ± 4.05
	P	0.242	0.698	0.496	0.357
rs5918 (ITGB3)	CC	176.18 ± 6.01	184.68 ± 8.08	76.93 ± 2.61	68.76 ± 2.38
	CT	178.25 ± 4.12	186.02 ± 6.38	77.17 ± 1.93	69.01 ± 1.64
	TT	179.92 ± 5.25	197.79 ± 10.02	78.11 ± 2.91	66.43 ± 2.54
	P	0.846	0.549	0.947	0.799
rs671 (ALDH2)	GG	170.28 ± 3.74	185.50 ± 11.97	74.33 ± 3.61	64.11 ± 3.26
	GA	175.88 ± 11.76	187.19 ± 6.18	75.88 ± 1.89	76.41 ± 1.86
	AA	180.77 ± 4.61	189.41 ± 7.23	79.37 ± 2.26	64.12 ± 1.72
	P	0.218	0.954	0.394	0.492
rs1800795 (IL-6)	GG	173.71 ± 7.17	182.02 6.13	72.03 ± 2.52	69.42 ± 3.96
	GC	175.51 ± 3.86	190.54 7.70	76.04 ± 1.99	68.01 ± 1.70
	CC	177.11 ± 5.14	197.06 10.28	80.47 ± 2.37	65.42 ± 1.76
	P	0.866	0.478	0.091	0.714
Genetic Risk Score (GRS) groups	Group I (GRS 0–2)	179.95 ± 5.94	196.13 ± 8.89	79.92 ± 3.94	55.41 ± 2.41
	Group II (GRS 3–5)	184.59 ± 2.44	204.08 ± 3.35	85.11 ± 1.54	51.04 ± 1.82
	Group III (GRS 6–8)	193.11 ± 5.49	212.60 ± 8.89	93.41 ± 3.20	49.12 ± 1.71
	P	0.012	0.001	0.005	1.5 × 10−3

Legend: Values for different lipid parameters are indicated as mean ± S.E Analysis of covariance with age and gender adjusted, p-values indicate the association pattern of the selected SNPs with different anthropometric traits