Table 2.
Category | Predictor | B (95% C.I.) | S.E. | β | t | p | sr 2 |
---|---|---|---|---|---|---|---|
Lifetime experience | LEQ young adulthood specific | −0.001 (−0.020, 0.018) | 0.010 | −0.007 | −0.090 | 0.928 | 0.000 |
LEQ young adulthood non-specific | 0.024 (−0.007, 0.054) | 0.015 | 0.131 | 1.533 | 0.127 | 0.011 | |
LEQ midlife specific | 0.026 (−0.005, 0.056) | 0.016 | 0.122 | 1.651 | 0.101 | 0.012 | |
LEQ midlife non-specific | 0.042 (0.013, 0.070) | 0.015 | 0.235 | 2.857 | 0.005 | 0.036 | |
Cognitive function | WAIS full-scale IQ | 0.001 (−0.013, 0.014) | 0.007 | 0.007 | 0.080 | 0.936 | 0.000 |
Episodic memory | 0.197 (0.036, 0.358) | 0.081 | 0.194 | 2.423 | 0.017 | 0.026 | |
Working memory | 0.184 (0.020, 0.349) | 0.083 | 0.192 | 2.217 | 0.028 | 0.022 | |
Executive function | 0.083 (−0.091, 0.257) | 0.088 | 0.090 | 0.943 | 0.347 | 0.004 | |
Language processing | 0.210 (0.038, 0.382) | 0.087 | 0.203 | 2.407 | 0.017 | 0.026 | |
Psychosocial function | LSNS family | −0.004 (−0.031, 0.023) | 0.014 | −0.023 | −0.285 | 0.776 | 0.000 |
LSNS neighbours | 0.001 (−0.027, 0.028) | 0.014 | 0.003 | 0.041 | 0.967 | 0.000 | |
LSNS friends | −0.014 (−0.045, 0.017) | 0.016 | −0.071 | −0.905 | 0.367 | 0.004 | |
HADS anxiety | −0.017 (−0.070, 0.036) | 0.027 | −0.050 | −0.64 | 0.523 | 0.002 | |
HADS depression | 0.012 (−0.061, 0.086) | 0.037 | 0.026 | 0.334 | 0.739 | 0.000 | |
Genetic | APOE | 0.127 (−0.153, 0.406) | 0.142 | 0.063 | 0.893 | 0.373 | 0.004 |
BDNF Val66Met | −0.019 (−0.301, 0.264) | 0.143 | −0.009 | −0.131 | 0.896 | 0.000 | |
KIBRA | 0.123 (−0.149, 0.395) | 0.138 | 0.064 | 0.894 | 0.373 | 0.004 | |
COMT Val158Met | 0.046 (−0.248, 0.340) | 0.149 | 0.022 | 0.308 | 0.759 | 0.000 | |
SERT 5-HTTLPR | 0.206 (−0.081, 0.494) | 0.146 | 0.099 | 1.416 | 0.159 | 0.009 |
C.I. confidence interval, sr 2 semi-partial correlation squared, LEQ Lifetime of Experiences Questionnaire, WAIS Wechsler Adult Intelligence Scale, LSNS Lubben Social Network Scale, HADS Hospital Anxiety and Depression Scale, APOE apolipoprotein E, BDNF brain-derived neurotrophic factor, KIBRA kidney and brain expressed protein, COMT catechol-O-methyl transferase, SERT serotonin transporter