Table 2.
Univariate and multivariate survival analysis for evaluating the effect of marital status on chondrosarcoma CSS in SEER database.
| Variable | 5-year CSS | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Log rank χ2 test | P | HR (95% CI) | P | ||
| Sex | 37.283 | <0.001 | |||
| Male | 76.9% | Reference | |||
| Female | 83.3% | 0.659 (0.577–0.753) | <0.001 | ||
| Age | 189.183 | <0.001 | |||
| <60 | 85.1% | Reference | |||
| ≥60 | 69.0% | 1.743 (1.520–1.998) | <0.001 | ||
| Race | 1.452 | 0.484 | NI | ||
| White | 79.7% | ||||
| Black | 79.2% | ||||
| Other | 80.6% | ||||
| Histotype | 576.205 | <0.001 | |||
| Chondrosarcoma, NOS | 83.3% | Reference | |||
| Myxoid | 79.0% | 0.989 (0.806–1.214) | 0.919 | ||
| Mesenchymal | 51.9% | 2.031 (1.560–2.644) | <0.001 | ||
| Dedifferentiated | 28.1% | 2.376 (1.892–2.984) | <0.001 | ||
| Other | 91.9% | 0.524 (0.280–0.983) | 0.044 | ||
| Pathological grade | 621.672 | <0.001 | |||
| Low-grade | 88.5% | Reference | |||
| High-grade | 50.6% | 2.719 (2.300–3.215) | <0.001 | ||
| Unknown | 71.4% | 1.845 (1.563–2.179) | <0.001 | ||
| Tumor location | 40.407 | <0.001 | |||
| Extremities | 82.6% | Reference | |||
| Axial | 74.6% | 1.176 (1.015–1.362) | 0.031 | ||
| Other | 81.1% | 0.760 (0.631–0.915) | 0.004 | ||
| Tumor size | 195.597 | <0.001 | |||
| <8 cm | 87.7% | Reference | |||
| ≥8 cm | 67.8% | 1.594 (1.353–1.879) | <0.001 | ||
| Unknown | 79.0% | 1.474 (1.245–1.745) | <0.001 | ||
| SEER stage | 1006.710 | <0.001 | |||
| Localized | 90.2% | Reference | |||
| Regional | 76.0% | 1.930 (1.647–2.263) | <0.001 | ||
| Distant | 35.4% | 4.847 (4.011–5.856) | <0.001 | ||
| Unstaged | 79.1% | 1.460 (1.119–1.904) | 0.005 | ||
| Socioeconomic status | 11.734 | 0.001 | |||
| Low-SES | 77.6% | Reference | |||
| High-SES | 81.9% | 0.863 (0.762–0.978) | 0.021 | ||
| Marital status | 67.442 | <0.001 | |||
| Married | 80.3% | Reference | |||
| Divorced | 78.4% | 1.367 (1.103–1.693) | 0.004 | ||
| Single | 84.0% | 0.892 (0.754–1.056) | 0.185 | ||
| Widowed | 62.3% | 1.516 (1.222–1.880) | <0.001 | ||
| Treatment | 625.543 | <0.001 | |||
| Surgery and radiation | 71.6% | Reference | |||
| Only surgery | 85.2% | 0.661 (0.560–0.780) | <0.001 | ||
| Only radiation | 23.3% | 2.264 (1.755–2.921) | <0.001 | ||
| None | 60.0% | 1.461 (1.155–1.848) | 0.002 | ||
SEER – Surveillance, Epidemiology, and End Results; CSS – cancer-specific survival; HR – hazard ratio; CI – confidence interval; NOS – not otherwise specified; SES – socioeconomic status; NI – not included in the multivariate survival analysis.