Figure 1.

Conceptual framework for Phase 1 of the AWI-Gen study. To begin to understand the cardiometabolic disease endpoints in the six sub-Saharan African communities, we collected data on non-modifiable biological factors and a host of mediators and potential confounders, including behavioural data and infection history and measures of body composition that include height, weight, waist and hip circumference (WC and HC), visceral and subcutaneous fat (VAT and SCAT) and carotid intima-media thickness (CIMT). Also measured were markers indicative of cardiometabolic disease (CMD) including blood pressure, glucose and insulin, urinary albumin protein and creatinine (UAPC) and serum creatinine (SC).