Table 1.
Current properties of CaV1.3-ΔE32 and CaV1.3-ΔE32-D4N. Numerical values represent mean ± SEM. Statistical differences between mutants and controls were determined with unpaired Student’s t-test. Difference against control is represented as *p ≤ 0.05; **p ≤ 0.01.
| Ipeak (pA/pF) | Significance (P value) | V1/2 (mV) |
Significance (P value) | Vrev (mV) | kact (mV) | Gmax (nS/nF) | Tau (ms) | Ires200/Ipeak | n | |
|---|---|---|---|---|---|---|---|---|---|---|
| CaV1.3-ΔE32 | −2.9 ± 0.6 | 0.7 ± 1.5 | 80.7 ± 4.9 | 7.6 ± 0.8 | 50.3 ± 8.4 | 1.9 ± 0.3 | 0.77 ± 0.04 | 9 | ||
| CaV1.3-ΔE32-D4N | −1.6 ± 0.2 | * (0.0368) | 6.1 ± 0.9 | ** (0.0056) | 74.6 ± 5.1 | 7.9 ± 0.4 | 35.5 ± 5.2 | 2.6 ± 0.3 | 0.75 ± 0.03 | 10 |