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. 2018 Jun 26;77(10):1516–1523. doi: 10.1136/annrheumdis-2017-212916

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Effect of B cell stimulation and iberdomide (CC-220) on Ikaros and Aiolos protein levels over time. (A) CD19+ B cells were isolated from the peripheral blood mononuclear cells of normal donors and stimulated in the presence of CC-220 or a Syk inhibitor. (B, C) Ikaros and Aiolos were measured by Western blot analysis. Representative blots are shown; graphs represent the mean and SE of the mean (n=3).