Biosensing principles using nanoparticles and nanomaterials.
Notes: (A) Electromechanical biodetection schematic for silver nanoparticles. (B) Quantum dot electromechanical detection of DNA strands. (C) Electrochemical detection schematic for silver nanoparticles. (D) Example of localized surface plasmon resonance modulation by altering nanoparticle compositions. (A) Reprinted by permission from Springer Nature: Anal Bioanal Chem. Aptamer-based electrochemical approach to the detection of thrombin by modification of gold nanoparticles. Li L, Zhao H, Chen Z, Mu X, Guo L. Copyright 2010.179 (B) Reprinted with permission from Wang J, Liu G, Merkoçi A. Electrochemical coding technology for simultaneous detection of multiple DNA targets. J Am Chem Soc. 2003;125(11):3214–3215. Copyright 2003 American Chemical Society.180 (C) Reprinted with permission from Li H, Sun Z, Zhong W, Hao N, Xu D, Chen HY. Ultrasensitive electrochemical detection for DNA arrays based on silver nanoparticle aggregates. Anal Chem. 2010;82(13):5477–5483. Copyright 2010 American Chemical Society.165 (D) Reprinted with permission from Doria G, Conde J, Veigas B, et al. Noble metal nanoparticles for biosensing applications. Sensors (Basel). 2012;12(2):1657–1687.181
Abbreviation: Abs, absolute.