Table 4.
GenoType MTBDRplus assay performance evaluation compared to MGIT 960 system
| MGIT 960 system
|
Total | Diagnostic performance of GenoType MTBDRplus assay
|
Level of agreement
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| R | S | Sensitivity | Specificity | PPV | NPV | k-value | ||||
| GenoType MTBDRplus assay | INH | R | 1 | 0 | 1 | 33.3 | 100 | 100 | 98.4 | 0.494 |
| S | 2 | 123 | 125 | |||||||
| RIF | R | 1 | 1 | 2 | 100 | 99.2 | 50 | 100 | 0.663 | |
| S | 0 | 124 | 124 | |||||||
| MDR | R | 1 | 0 | 1 | 100 | 100 | 100 | 100 | 1.00 | |
| S | 0 | 125 | 125 | |||||||
Abbreviations: R, resistant; S, susceptible; PPV, positive predictive value; NPV, negative predictive value; INH, isoniazid; RIF, rifampicin; MDR, multidrug resistance.