Figure 3. Identification of gene markers for HER2+, Luminal A/B and TNBC.
(A) Marker heatmap showing the expression (z-score of log2 counts) of 112 marker genes. Each row represents the expression of a single gene across each patient sample (columns). The rows of the heatmap are ordered identically to the receptor heatmap in Figure 1. (B-E) Expression of a representative identified marker across molecular subtypes is shown for each of the four identified marker groups. Each plot provides the distribution of log2 expression values of AR (B), SOX10 (C), PGR (D) and HER2 (E) across subtypes. The black line represents the median expression value for each subtype.