Table 1. Peptide stability energies of the peptides in kcal/mol.
Peptide | ∆Hstability (kcal/mol) | ∆∆H rel (kcal/mol) |
---|---|---|
L-ArgPEP | −731.4 ± 14.9 | +11.2 |
D-ArgPEP | −742.6 ± 16.6 | 0.0 |
(P)L-ArgPEP | −598.0 ± 16.9 | +14.5 |
(P)D-ArgPEP | −612.5 ± 16.1 | 0.0 |
Note: The (P) designates “Protected”. ∆∆H rel = E(DARG) - E(Pep). Overall, the non-protected peptides are predicted to be more stable in water than the protected peptides.