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. Author manuscript; available in PMC: 2019 Oct 1.

Published in final edited form as: Am J Clin Dermatol. 2018 Oct;19(5):759–769. doi: 10.1007/s40257-018-0381-6

Figure 2. — Conceptual model of itch. The five primary components of the Wilson and Cleary model are color coded: 1) biological and physiological variables , 2) symptom status including itch, scratch, pain and sleep disturbance , 3) functional status including functional limitations and task avoidance , 4) general health perceptions , and 5) health related quality of life . Additional itch-specific modifications of the model include stigma, social life and relationship problems, emotional disturbances, treatment burden and treatment response. Each of these steps in the model are potentially modified characteristics of the individual including activity motivation, emotional response to itch and baseline vitality and characteristics of the environment including climate, irritants, stressors and occupation .

Inline graphic — Conceptual model of itch. The five primary components of the Wilson and Cleary model are color coded: 1) biological and physiological variables , 2) symptom status including itch, scratch, pain and sleep disturbance , 3) functional status including functional limitations and task avoidance , 4) general health perceptions , and 5) health related quality of life . Additional itch-specific modifications of the model include stigma, social life and relationship problems, emotional disturbances, treatment burden and treatment response. Each of these steps in the model are potentially modified characteristics of the individual including activity motivation, emotional response to itch and baseline vitality and characteristics of the environment including climate, irritants, stressors and occupation .