Fig 5. Zeaxanthin treatment improved structure of photoreceptor outer segments and the RPE.

SD-OCT image of retinas from the zeaxanthin treated groups (n = 11) (B) after four months of treatment (6 months of age) shows preserved RPE layer and outer segment layer compared to eyes from untreated mice (n = 8) (A) of same age. We did not see any significant change in retinal outer nuclear layer (ONL) thickness (C) between control untreated and zeaxanthin-treated group. The red arrow indicates the RPE layer and the green arrow indicates the region of the photoreceptor outer segments.