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. 2018 Sep 28;13(9):e0203195. doi: 10.1371/journal.pone.0203195

Table 3. First pregnancy factors associated with increased risk of severe maternal morbidity in a second birth, amongst women with a first and second birth.

Severe maternal morbidty
n(%)
aRRe 95% Confidence Interval p- value
Private Insurance Yes 408/ 87759 (0.5) 0.9 (0.8, 1.0) 0.2
No 673/ 139488 (0.5) Ref f
Australian born Yes 779/ 162402 (0.5) 1 (0.9, 1.2) 0.7
No 302/ 64845 (0.5) Ref
Smoker Yes 108/ 21348 (0.5) 1.1 (0.9, 1.4) 0.3
No 970/ 205290 (0.5) Ref
Any ARTa Yes 50/ 8205 (0.6) 1.1 (0.8, 1.5) 0.5
No 1031/ 219042 (0.5) Ref
Pregnancy hypertension Yes 157/ 24472 (0.6) 1.3 (1.1, 1.6) <0.01
No 924/ 202775 (0.5) Ref
Chronic hypertension Yes 16/ 1674 (1.0) 1.5 (0.9, 2.5) 0.2
No 1065/ 225573 (0.5) Ref
Gestational diabetes Yes 67/ 11646 (0.6) 1.2 (0.9, 1.5) 0.3
No 1014/ 215601 (0.5) Ref
Chronic conditions Yes 76/ 5610 (1.4) 2.8 (2.2, 3.6) < .0001
No 1005/ 221637 (0.5) Ref
Large for gestational age Yes 110/ 17495 (0.6) 1.3 (1.1, 1.6) 0.02
No 971/ 209752 (0.5) Ref
Morbidly adherent placenta Yes 5/ 428 (1.2) 1.8 (0.8, 4.3) 0.3
No 1076/ 226819 (0.5) Ref
Placenta praevia Yes 23/ 1644 (1.4) 2.5 (1.6, 3.8) <0.01
No 1058/ 225603 (0.5) Ref
Maternal age Under 20 66/ 16631 (0.4) 0.8 (0.6, 1.1) <0.01
20–34 862/ 188582 (0.5) Ref
35+ 153/ 21999 (0.7) 1.5 (1.2, 1.8)
Socioeconomic status Highest disadvantage 199/ 44950 (0.4) 0.9 (0.8, 1.1) 0.2
2 181/ 42651 (0.4) 0.9 (0.7, 1.1)
3 229/ 42426 (0.5) 1.1 (0.9, 1.3)
4 218/ 44902 (0.5) 1.0 (0.8, 1.2)
Highest SESc 247/ 50191 (0.5) Ref
PPHb Type** +PPH+RBCd 24/ 2399 (1.0) 2.0 (1.3, 3.0) <0.01
+PPH–RBC 103/ 16869 (0.6) 1.3 (1.0, 1.6)
-PPH+RBC 11/ 491 (2.2) 4.1 (2.2, 7.4)
-PPH-RBC 943/ 207488 (0.5) Ref
Year of birth 1 (1.0, 1.0) 0.2

aART: Assisted reproductive technology;

bPPH: Postpartum haemorrhage;

cSES: socioeconomic status;

dRBC, Red blood cell;,

eaRR: Adjusted Relative Risk.

fRef: reference category

** +RBC +PPH: Transfusion and haemorrhage; +RBC-PPH: Transfusion without haemorrhage; -RBC +PPH: Haemorrhage without transfusion;-RBC–PPH: neither haemorrhage nor transfusion.