Table 1. Patient characteristics at baseline.
P-values reflect fibrosis stage comparisons.
| Overall (n = 86) |
Mild NAFLD (n = 47) |
Advanced NAFLD (n = 39) |
p-value | |||
|---|---|---|---|---|---|---|
| Fibrosis Stage | F0 (n = 17) |
F1 (n = 30) |
F3 (n = 30) |
F4 (n = 9) |
||
| Gender (% female) | 58 (67.4) | 11 (64.7) | 18 (60.0) | 2 (73.3) | 7 (77.8) | 0.63 |
| Age, mean±SD | 50.9 ± 10.6 | 51.1 ± 9.1 | 50.6 ± 10.7 | 48.3 ± 10.8 | 59.7 ± 8.7 | 0.50 |
| Race | 0.64 | |||||
| White (%) | 77 (89.5) | 15 (88.2) | 27 (90.0) | 27 (90.0) | 8 (88.9) | |
| Black (%) | 6 (7.0) | 2 (11.8) | 1 (3.3) | 2 (6.7) | 1 (11.1) | |
| Body Mass Index (kg/m2) mean ± SD | 36.3 ± 8.9 | 35.4 ± 8.3 | 35.8 ± 8.9 | 36.9 ± 7.9 | 37.5 ± 13.2 | 0.43 |
| Diabetes Mellitus (%) | 36 (41.9) | 4 (23.5) | 7 (23.3) | 18 (60.0) | 7 (77.8) | 0.001 |
| Hyperlipidemia (%) | 55 (63.9) | 14 (82.4) | 19 (63.3) | 18 (60.0) | 4 (44.4) | 0.24 |
| Hypertension (%) | 54 (62.8) | 11 (64.7) | 16 (53.3) | 19 (63.3) | 8 (88.9) | 0.28 |
| Smoking (%) | 6 (7.7) | 2 (11.8) | 1 (3.8) | 3 (11.5) | 0 | 0.52 |
| NAFLD Activity Score (NAS) > = 5 | 34 (39.5) | 2 (11.8) | 11 (36.7) | 19 (63.3) | 2 (22.2) | 0.003 |
| Hemoglobin A1c (%), mean ± SD | 6.32 ± 1.0 | 5.9 ± 0.5 | 6.1 ± 1.2 | 6.6 ± 1.2 | 6.5 ± 0.8 | 0.033 |
SD, standard deviation