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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2016 Dec 9;1862(11):1404–1413. doi: 10.1016/j.bbalip.2016.11.015

Fig. 3. Scheme of lysophospholipid remodeling mediated by the LplT-Aas system.

Fig. 3

LplT substrates LPE, LPG, diacyl-CL and deacylated CL (CL-hg) are transported by LplT from the periplasm to the inner leaflet of the IM by an energy-independent mechanism. On the cytoplasmic surface, bifunctional Aas catalyzes acyl transfer to a flipped LPL using acyl-ACP as acyl donor, generating PE, PG or triacyl-CL respectively. Aas also catalyzes ATP-dependent synthesis of acyl-ACP using a fatty acid. LPA, LPC and glycerol-3-phosphate (G3P) are not LplT substrates.