Table 1.
Demographic, cognitive, genetic and biomarker data
| NC (n = 394) Mean (SD) | MCI (n = 816) Mean (SD) | t/χ2 | P | |
|---|---|---|---|---|
| Age | 74.83 (5.73) | 73.06 (7.47) | 4.16 | < .001 |
| Years of education | 16.30 (2.73) | 15.92 (2.86) | 2.32 | .026 |
| Sex (M/F) | 204/190 | 483/333 | 5.95 | .015 |
| MMSE | 29.06 (1.14) | 27.56 (1.82) | 14.91 | < .001 |
| AVLT baseline | 12.82 (2.42) | 10.49 (3.48) | 11.91 | < .001 |
| AVLT 6-months | 12.66 (2.44) | 10.06 (3.65) | 12.82 | < .001 |
| Ethnicity | ||||
| Not hispano/latino, n (%) | 378 (95.9) | 787 (96.4) | ||
| Hispano/latino, n (%) | 14 (3.6) | 25 (3.1) | ||
| Unknown, n (%) | 2 (0.5) | 4 (0.5) | 0.21 | .902 |
| Married, n (%) | 268 (68) | 632 (77.5) | 19.28 | .001 |
| APOE ε4 | ||||
| 0, n (%) | 287 (72.8) | 397 (48.7) | ||
| 1, n (%) | 96 (24.4) | 327 (40.1) | ||
| 2, n (%) | 11 (2.8) | 92 (11.3) | 68.72 | < .001 |
| FDG-PET | 130.70 (11.47) | 124.43 (13.44) | 6.71 | < .001 |
NC: normal cognition. MCI: mild cognitive impairment. MMSE: Mini-Mental State Examination. AVLT: Auditory Verbal Learning Test. FDG-PET: fluorodeoxyglucose positron emission tomography. APOE: apolipoprotein E