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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Neurobiol Aging. 2018 Jul 24;71:105–114. doi: 10.1016/j.neurobiolaging.2018.07.012

Figure 3. T cell markers are regulated by aging and M. vaccae.

Figure 3

(A) CD3 mRNA expression was upregulated in the hippocampus of aged as compared to young rats and reduced by M. vaccae immunization. (B) CD4 mRNA expression was upregulated in the aged rat hippocampus and (B) Foxp3 mRNA expression was elevated in aged rats by M. vaccae treatment. Results were analyzed using a 2 × 2 × 2 ANOVA with age, surgery, and M. vaccae treatment as between-subjects factors (n = 6-7/group). Data are expressed as mean ± SEM. *p < 0.05.