Table 1.

Participant characteristics at baseline for longitudinal sample ( $\ge$ 2 visits); age, education, body mass index (BMI), years smoking, Mini-Mental State Examination (MMSE), number of visits, time between first and last visit listed as average (standard deviation).

Characteristics	AD n=1899	DLB n=65	FTD n=168	VaD n=13	Normal n=3583	p-value**
Age	74.9 (9.2)	71.0 (7.7)	64.2 (8.4)	73.1 (9.3)	70.3 (9.6)	<0.0001
Sex, female, %	50.1	13.9	30.4	30.8	65.6	<0.0001
Race, %						0.0004
White	85.3	95.4	92.9	76.9	81.5
Black or African American	9.8	3.1	2.4	15.4	13.9
American Indian or Alaska Native	0.4	0.0	0.0	0.0	0.2
Native Hawaiian or Pacific Islander	0.0	0.0	0.0	0.0	0.0*
Asian	1.9	0.0	3.0	0.0	1.8
Multiracial	2.7	1.5	1.8	7.7	2.6
Education	14.7 (3.5)	15.0 (3.4)	15.1 (2.9)	15.2 (3.2)	15.8 (2.9)	<0.0001
BMI	26.1 (4.3)	26.9 (3.8)	28.0 (5.0)	28.8 (8.8)	27.4 (5.3)	<0.0001
Years smoking	10.2 (15.2)	11.6 (15.3)	10.0 (14.6)	21.5 (26.5)	9.3 (14.2)	0.0096
Atrial fibrillation, recent/active, %	4.4	9.2	5.4	7.7	3.6	0.0964
Diabetes, recent/active, %	8.7	6.2	8.3	30.8	9.0	0.0745
Hypertension, recent/active, %	46.6	38.5	33.3	84.6	45.5	0.0004
Hypercholesterolemia, recent/active, %	50.4	56.9	44.1	53.9	44.7	0.0005
MMSE	22.4 (4.6)	23.7 (4.2)	23.6 (5.7)	23.9 (4.5)	29.1 (1.2)	<0.0001
CDR-SUM	4.9 (2.7)	4.9 (2.9)	4.6 (3.2)	4.8 (3.0)	0.0* (0.2)	<0.0001
Number of visits	4.0 (1.2)	3.6 (1.0)	3.7 (1.0)	3.5 (0.7)	5.2 (2.0)	<0.0001
Months between first and last visit	40.1 (17.0)	35.6 (13.7)	37.7 (16.9)	36.9 (12.0)	58.8 (25.8)	<0.0001

^*: due to rounding, percentage is 0.0

^**: p-value calculated using analysis of variance (ANOVA) for continuous variables and ${\chi }^2$ test for difference of proportions for categorical variables across all the groups