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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Curr Alzheimer Res. 2018;15(11):1032–1044. doi: 10.2174/1567205015666180702105119

Table 2.

Model results for the impact of cardiovascular risk factors (CRF) on the change in Mini-Mental State Examination (MMSE) per month for each of the diagnoses of interest.

AD
n=1899, nt=7519
DLB
n=65, nt=236
FTD
n=168, nt=626
VaD**
n=13, nt=45
Normal
n=3583, nt=18468
CRF Est. SE p-value Est. SE p-value Est. SE p-value Est. SE p-value Est. SE p-value
BMI 0.0006 0.0005 0.2294 −0.0027 0.0045 0.5514 0.0092 0.0023 <0.0001 −0.0016 0.0042 0.6975 0.0001 0.0001 0.3265
Years Smoking 0.0002 0.0001 0.2048 0.0029 0.0012 0.0144 0.0023 0.0006 0.0003 0.0015 0.0013 0.2496 0.0000* 0.0000* 0.4473
Atrial Fibrillation 0.0069 0.0093 0.4569 −0.0643 0.0632 0.3096 0.0954 0.0400 0.0174 −0.0675 0.1624 0.6811 −0.0010 0.0011 0.3980
Diabetes 0.0081 0.0070 0.2492 0.0740 0.0892 0.4074 0.0463 0.0348 0.1836 −0.0068 0.0661 0.9194 0.0014 0.0009 0.1297
Hypertension 0.0177 0.0044 <0.0001 0.0235 0.0318 0.4618 −0.0384 0.0253 0.1300 0.0094 0.1383 0.9465 −0.0027 0.0006 <0.0001
Hyperchol. 0.0100 0.0044 0.0241 −0.0447 0.0301 0.1393 0.0050 0.0230 0.8271 −0.0313 0.0958 0.7467 0.0001 0.0005 0.8885

n=number of subjects, nt=total number of visits/observations

*

: due to rounding, estimate (Est.) or standard error (SE) is 0.00

**

: due to a small sample size, caution should be used in interpreting the results.