Table 3.

Model results for the impact of cardiovascular risk factors (CRF) on the change in Clinical Dementia Rating Sum of Boxes (CDR-SUM) per month for each of the diagnoses of interest.

	AD n=1899, nt=7519			DLB n=65, nt=236			FTD n=168, nt=626			VaD** n=13, nt=45			Normal n=3583, nt=18468
CRF	Est.	SE	p-value	Est.	SE	p-value	Est.	SE	p-value	Est.	SE	p-value	Est.	SE	p-value
BMI	−0.0005	0.0003	0.0816	−0.0024	0.0026	0.3575	−0.0034	0.0013	0.0126	−0.0025	0.0025	0.3227	0.0000*	0.0000*	0.8975
Years Smoking	−0.0001	0.0001	0.1295	−0.0005	0.0007	0.4486	−0.0008	0.0004	0.0288	0.0009	0.0008	0.2404	0.0000*	0.0000*	0.3073
Atrial Fibrillation	−0.0016	0.0059	0.7848	−0.0070	0.0368	0.8495	−0.0406	0.0234	0.0838	−0.0032	0.0965	0.9739	0.0001	0.0002	0.5026
Diabetes	0.0019	0.0044	0.6647	−0.0648	0.0521	0.2154	−0.0250	0.0204	0.2210	0.0932	0.0399	0.0279	−0.0001	0.0002	0.6964
Hypertension	−0.0109	0.0028	0.0001	−0.0036	0.0184	0.8436	0.0019	0.0149	0.8967	0.0205	0.0789	0.7972	0.0002	0.0001	0.0661
Hyperchol.	−0.0061	0.0028	0.0294	0.0521	0.0175	0.0032	−0.0155	0.0136	0.2546	0.0240	0.0527	0.6534	−0.0001	0.0001	0.2466

n=number of subjects, nt=total number of visits/observations

^*: due to rounding, estimate (Est.) or standard error (SE) is 0.00

^**: due to a small sample size, caution should be used in interpreting the results.