. Author manuscript; available in PMC: 2020 Mar 1.

Published in final edited form as: Pediatr Nephrol. 2018 Mar 28;34(3):405–412. doi: 10.1007/s00467-018-3946-y

Table 4.

Target Organ Damage Definitions

	European Guidelines		US Guidelines
	Screening	How defined?	Screening	How defined?
Electrocardiography	No		No
Echocardiography
* LVH	Yes	LVMI ≥ 95^th %ile	Yes	LVMI ≥ 51 g/m^2.7 for children > 8 years (boys and girls) or LVM > 115g/BSA for boys and LVM > 95g/BSA for girls
* LV Wall Thickness	Yes	RWT ≥ 95^th %ile	Yes	RWT >0.42 cm, LV wall thickness >1.4
* Ejection Fraction	No		Yes	EF<53%
Measures of Arterial Stiffness: Pulse Wave Velocity	No		No
Measures of Arterial Structure: Carotid intima media thickness	Yes	cIMT ≥95^th %ile by age and sex

US=United States; LVH = left ventricular hypertrophy; LVM=left ventricular mass; LVMI=left ventricular mass index; LV=left ventricular; PWV=pulse wave velocity; RWT=relative wall thickness; EF=ejection fraction; cIMT=carotic intima media thickness