Fig. 2.

Structural comparison of different catalytic states of CotB2. Residues of the DDXD motif are labelled with red letters, residues of the NSE/DTE motif with yellow letters, respectively. Water molecules are depicted as red spheres. Hydrogen bonds are indicated by dashed lines. a Catalytic centre of CotB2^wt•Mg²⁺₃•F-Dola. Mg²⁺-ions are depicted as green spheres. Solid lines represent the coordination sphere of the Mg²⁺-ions. b Comparison of CotB2^wt•Mg²⁺₃•F-Dola shown in magenta and CotB2^wt•Mg²⁺_B•GGSDP shown in cyan. c Comparison of CotB2^F107A•Mg²⁺_B shown in pale purple and CotB2^wt•Mg²⁺_B•F-Dola shown in cyan