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. 2018 Sep 7;9(9):450. doi: 10.3390/genes9090450

Figure 7.

Figure 7

Chemical inhibition of full-length phosphorylated Akt1 variants. Inhibition of (A) pAkt1S473, (B) pAkt1T308, and (C) ppAkt1T308,S473 with varying concentrations (0.001, 0.05, 0.5, 1, 5, 10 μM) of Akti-1/2 inhibitor VIII. The resulting IC50 values are in Table 4.