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. 2018 Aug 22;9(9):426. doi: 10.3390/genes9090426

Figure 2.

Figure 2

Experimental confirmation of predicted competition between miRNAs and RBPs. (a) SRSF2 and MALAT1 expression in TE1 cells treated with two small interfering RNA (siRNA)-SRSF2 and control siRNAs. (b) Quantitative real time polymerase chain reaction (qRT-qPCR) for MALAT1 in TE1 cells after transfection with miR-101, miR-383 and miR-502. (c) qRT-PCR of MALAT1 in TE1 cells after co-transfection with both siRNA-SRSF2 and miRNAs. (d) qRT-PCR of MALAT1 in TE1 cells after co-transfection with both siRNA-SRSF2 and miRNAs inhibitors. * p < 0.05, ** p < 0.01, *** p < 0.001. The concentrations of miRNA mimics were tested at both 30 nM and 50 nM. The concentrations of miRNA inhibitors were tested at 100 nM. Data are the means ± standard error of mean (s.e.m.) of three experiments.