Specification and patterning of the Drosophila antenna. (A) Model of progressive specification of the eye and antenna territories and P-D subdivision of the antenna disc. Schematic representation of three representative stages of EAD development is shown. In each disc the expression and interactions of genes and signaling pathways required for eye and antenna field specification are schematized. (B) The antenna and leg appendages are homologous structures. Arrows indicate the correspondence between the antenna and leg domains (Postlethwait and Schneiderman, 1971). The expression of the P-D genes Dll, dac, and hth and their overlapping domains are represented by a color code. Compare the relative expression of Dll, dac, and hth in the antenna and the leg imaginal discs. Note that hth and Dll coexpress in a large domain in the antenna while in the leg these genes are expressed in almost exclusive domains.