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. 2018 Aug 30;7(9):116. doi: 10.3390/antiox7090116

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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STRING analysis of proteins identified as targets of OxPAPC from the PBS-insoluble/RIPA-soluble fraction (A) and from the PBS-soluble fraction (B). The RIPA-soluble fraction of modified proteins contains mainly proteins located at membrane organelles (green nodes: membrane-bounded organelle; GO: 0043227). Furthermore, several modified proteins are located at the mitochondrial membrane (blue nodes: mitochondrial part; GO: 0044429). In the PBS-soluble fraction, proteins related to protein folding (red nodes: protein folding; GO: 0006457) and proteins related to the cytoskeleton (blue nodes: structural constituent of cytoskeleton; GO: 0005200) are enriched.