Table 4.

Effect of cysteamine hydrochloride on the serum parameters of oxidation and inflammation of broiler chickens challenged with Clostridium perfringens

			PC + CSH, g/kg of diet				Dose trends (P-values)
Items	NC	PC	100	150	200	SEM	Linear	Quadratic
Oxidative parameters
DAO, U/liter	0.70d	2.21a	1.08b	0.99bc	0.97c	0.026	0.002	0.226
MDA, nmol/liter	2.78c	5.02a	4.21b	4.08b	3.98b	0.058	0.006	0.760
PCO, nmol/g	22.91d	37.57a	31.33b	29.43bc	28.01c	0.560	0.001	0.739
Inflammatory factors
IL-1β, ng/liter	42.54d	133.6a	98.76b	82.60c	75.46c	2.300	<0.001	0.077
IL-6, ng/liter	58.68c	154.5a	110.8b	111.7b	103.2b	2.513	0.083	0.204
TNF-α, ng/liter	34.84d	125.8a	80.10b	80.29b	68.27c	1.647	<0.001	0.001

^a–d Means within a row with no common superscripts are significantly different (P < 0.05).

CSH, cysteamine hydrochloride; DAO, diamine oxidase; IL-1β, interleukin-1β; IL-6, interleukin-6; MDA, malondialdehyde; NC, negative control, without C. perfringens challenge; PC, positive control, challenged with C. perfringens; PCO, protein carbonyl; TNF-α, tumor necrosis factor-α.