Table 3.
Information of 6 selected age-related CpG sites.
| CpG ID | Gene ID | Chromosome Location 1 | Gene Region 2 | Relation to GpG Island 3 | Correlation Status | Reference |
|---|---|---|---|---|---|---|
| cg09809672 | EDARADD | 1:236557682 | TSS1500 | N_Shore | Negative | [1,17,33] |
| cg22736354 | NHLRC1 | 6:18122719 | 1stExon | Island | Positive | [2,7,18,19] |
| cg02228185 | ASPA | 17:3379567 | 1stExon | -- | Negative | [7,26,33] |
| cg01820374 | LAG3 | 12:6882083 | Body | N_Shore | Negative | [1] |
| cg06493994 | SCGN | 6:25652602 | 1stExon | Island | Positive | [2,7,18,19] |
| cg19761273 | CSNK1D | 17:80232096 | TSS1500 | S_Shore | Negative | [2] |
1 Chromosome location is referred to the Human genome reference GRCh37 version. 2 TSS: transcription start site. TSS1500: 1500 bp flanking region from the TSS. 3 CpGs island table were downloaded from University of California Santa Cruz (UCSC) browser. Distance of 2kb to CpG islands were defined as CpG island shores (N_Shore: downstream of CpG island and S_Shore: up-stream of the CpG island).