Table 3.
Features of general and disease-specific perioperative complications for patients with neuromuscular disease.
| Perioperative Complications in Patients with NMDs | |
|---|---|
| General issues | Features |
| Respiratory | Hypoxia, atelectasis |
| Hypercarbia | |
| Pneumonia (aspiration) | |
| Respiratory failure | |
| Cardiac | Arrhythmia |
| Ventricular dysfunction | |
| Disease-specific issues | Features |
| Malignant hyperthermia Associated with CCD, MmD, King–Denborough syndrome, other congenital myopathies |
Hyperkalemia |
| Muscle rigidity | |
| Acidosis | |
| Hyperthermia | |
| Rhabdomyolysis More likely with muscular dystrophies |
Hyperkalemia |
| Acute kidney injury | |
| Metabolic disturbance More likely with mitochondrial disease |
Hypoglycemia |
| Lactic acidosis | |
| Propofol infusion syndrome More likely with mitochondrial disease |
Lactic acidosis |
| Rhabdomyolysis | |
| Lipidemia | |
| Bradycardia | |
NMD: neuromuscular disorder, CCD: central core disease, MmD: multiminicore disease.