Table 3.
Association between the expression of the microRNAs (miRNAs) and the clinical pathological features (n = 80) c.
| Clinical Variable | LMS | CS | ESS | |||
|---|---|---|---|---|---|---|
| miRNA | p | miRNA | p | miRNA | p | |
| Age (over 50 years old) | 220c-3p a 29a-3p b |
0.049 0.033 |
- | - | - | - |
| Main complaint—Bleeding | - | - | - | - | 142-5p a 148b-3p a 214-3p a |
0.031 0.016 0.016 |
| Menopause | 148a-3p a 7-5p a 32-5p a |
0.022 0.023 0.030 |
30c-5p b,* 148a-3p b 100-5p b let-7i-5p b,* |
0.001 0.004 0.034 0.001 |
335-5p b | 0.025 |
| Oral contraceptive | - | - | - | - | 132-3p b 34c-5p b |
0.005 0.006 |
| HRT | - | - | - | - | 125a-5p b 222-3p b 205-5p b |
0.039 0.039 0.019 |
| Smoking | - | - | 125a-5p a 30c-5p a 135b-5p a let-7i-5p a 27b-3p a 29a-3p a let-7f-5p a 34a-5p a 25-3p a 125b-5p a 23b-3p a 335-5p a 21-5p a |
0.018 0.018 0.011 0.006 0.011 0.044 0.018 0.011 0.007 0.028 0.028 0.044 0.029 |
27b-3p a 143-3p a |
0.006 0.038 |
| Patients who died | 96-5p b 132-3p b 183-5p b,* 124-3p b |
0.023 0.026 0.001 0.024 |
122-5p a | 0.025 | 29b-3p b 206 b |
0.027 0.026 |
| Presence of relapse | 148a-3p a 29b-3p a 301a-3p b 29a-3p a 144-3p b |
0.021 0.008 0.027 0.040 0.020 |
335-5p b 96-5p b 378a-3p b 130a-3p b 183-5p b 134-5p b 7-5p b 128-3p b 18a-5p b 203a-3p b 32-5p b |
0.050 0.008 0.028 0.046 0.010 0.016 0.040 0.026 0.033 0.020 0.008 |
301a-3p b | 0.041 |
| 127-5p b | 0.045 | |||||
| Presence of metastasis | 140-5p a 193b-3p a let-7i-5p a 27b-3p a 143-3p a 125b-5p a |
0.002 0.002 0.034 0.029 0.004 0.025 |
- | - | 193b-3p b 210-3p b |
0.015 0.044 |
| Stage I | - | - | - | - | - | - |
| Stage II | - | - | 335-5p a,* 218-5p a |
0.001 0.014 |
23b-3p a | 0.017 |
| Stage IV | - | - | - | - | 7-5p b | 0.014 |
| High histological grade | let-7a-5p a 125a-5p b 222-3p b 148b-3p b 92a-3p b let-7b-5p a 205-5p b 20a-5p b 30c-5p b let-7g-5p a let-7c-5p a let-7e-5p a let-7f-5p b 218-5p b,* 100-5p b 155-5p b 1-3p b 191-5p b let-7d-5p b 15b-5p b 98-5p b 25-3p b 128-3p b 143-3p b 19a-3p b 23b-3p b 16-5p b 17-5p b 18a-5p b 27b-3p b |
0.008 0.047 0.040 0.050 0.029 0.009 0.010 0.008 0.031 0.005 0.029 0.014 0.045 0.001 0.044 0.012 0.011 0.024 0.010 0.002 0.002 0.010 0.041 0.047 0.031 0.017 0.033 0.034 0.049 0.020 |
184 a,* | 0.001 | - | - |
a miRNAs downregulated associated with the clinical variable (p < 0.05); b miRNAs upregulated associated with the clinical variable (p < 0.05); c Some sample data were not available; * p < 0.001.