Figure 2.

Ketogenic diet-fed mice had increased serum ketones, body weight, and fat weight than chow-fed mice. (A) Serum ketone bodies of mice fed a chow or ketogenic diet. Mouse serum was collected at study completion (48 weeks). Data analysed by Mann–Whitney test (p < 0.001, bars represent median values). (B) Fold change in body weights of mice fed a chow or ketogenic diet (fold change is body weights at 48 weeks divided by body weights at 39 weeks). Data analysed by Mann–Whitney test (p < 0.001, bars represent median values). (C) Subcutaneous (s.c.) fat pad weights (1 fat pad per mouse) of mice fed chow or ketogenic diet. Data analysed by Mann–Whitney test (p = 0.001, bars represent median values). (D) Gonadal fat weights of mice fed chow or ketogenic diet. Data analysed by Mann–Whitney test (p < 0.001, bars represent median values). n = 7 for all analyses.