Table 2.
Recommendations for the Treatment of Invasive Pulmonary Aspergillosis.
| Targeted Treatment of Invasive Pulmonary Aspergillosis in Hematologic Malignancy | |||||
| Voriconazole | Isavuconazole | Itraconazole | Liposomal Amphotericin B | Echinocandins | |
| ECIL-6 (61) | AI | AI | CIII | BI | CII |
| ESCMID (60) | AI-AII | AI-AII | CII-CIII | BII | CII-CIII |
| IDSA (83) | AI | AII | - | AII | AII (not recommended) |
| Salvage Treatment for Invasive Pulmonary Aspergillosis in Hematologic Malignancy | |||||
| Voriconazole | Isavuconazole | Itraconazole | Liposomal Amphotericin B | Posaconazole | |
| ECIL-6 (61) | BII | BII | CIII | BII | BII |
| ESCMID (60) | AII | AII | CII-DIII | BII | BII |
| IDSA (83) | - | - | AII | AII | AII |
| Combination Treatment for Invasive Pulmonary Aspergillosis in Hematologic Malignancy | |||||
| Voriconazole + Echinocandin | Other combinations | ||||
| ECIL-6 (61) | CI | CIII | |||
| ESCMID (60) | CI-CII | DIII | |||
| IDSA (83) | CII | CII | |||
| Targeted Treatment of Chronic Pulmonary Aspergillosis | |||||
| Voriconazole | Isavuconazole | Itraconazole | Liposomal Amphotericin B | Posaconazole | |
| ECIL-6 (61) | - | - | - | - | - |
| ESCMID (60) | AII | - | AII | - | BII |
| IDSA (83) | - | - | Preferred | - | - |