Table 1.
Baseline clinical characteristics of patients with idiopathic nephrotic syndrome.
| Idiopathic MCD | Idiopathic FSGS | p | ||
|---|---|---|---|---|
| n | Total | 97 | 68 | - |
| <30 years | 26.80% | 13.20% | ||
| 30–59 years | 39.20% | 48.50% | ||
| ≥60 years | 34% | 38.20% | ||
| Age | Median (IQR) | 47 (27.5–64) | 57 (42.2–66.7) | 0.01 |
| Sex ratio | Men/women | 55/42 | 48/20 | - |
| Hypertension | Total | 48.80% | 46.30% | 0.8 |
| <30 years | 21.70% | 33.30% | ||
| 30–59 years | 53.30% | 25% | ||
| ≥60 years | 35.50% | 80% | ||
| Body mass index | Median | 27 | 29 | 0.27 |
| (IQR) | (23–30) | (25–33) | ||
| Genetic factor | Research Identification | 7 (7.2%) | 1 (1.5%) | - |
| 1 (1%) | 0 | |||
| Familial INS | 4 (4.1%) | 0 | - | |
| Thrombosis history | Venous | 3 (3.1%) | 1 (1.5%) | - |
| Arterial | 3 (3.1%) | 5 (7.3%) | ||
| Cardiovascular risk factors | Median | 1 | 1 | - |
| (IQR) | (0–1.5) | (1–2) | ||
| Initial eGFR (MDRD, mL/min/1.73 m2) | Median (IQR) | 79 (49–103) | 42.5 (29–58) | <0.0001 |
| ≥90 | 36.80% | 6.20% | ||
| 60–89 | 28.70% | 12.50% | ||
| 30–59 | 26.50% | 51.60% | ||
| 15–29 | 3.40% | 28.10% | ||
| <15 | 4.60% | 1.60% | ||
| Proteinuria (g/day) | Median | 6.5 | 6 | 0.4 |
| (IQR) | (4.2–11) | (3.9–9) | ||
| Albuminemia (g/L) | Median (IQR) | 21 (16–23.5) | 29 (23–37) | <0.0001 |
| <30 g/L | 88.20% | 51.20% | ||
| <20 g/L | 42.30% | 13.90% | ||
| Cholesterol (g/L) | Median | 3.7 | 2.6 | - |
| (IQR) | (2.4–5) | (1.8–3.4) | ||
| Triglycerides (g/L) | Median | 1.9 | 2 | - |
| (IQR) | (1.2–2.7) | (1–3) |
FSGS, focal segmental glomerulosclerosis; MCD, minimal change disease; IQR, interquartile range; eGFR, estimated glomerular filtration rate; MDRD, modification of diet in renal disease; INS, idiopathic nephrotic syndrome.