Table 1.
Characteristics of the Study Population
| Characteristic | Control Subjects n = 2182 |
EA n = 2284 |
Control Subjects vs EA P valuea |
BE n = 3104 |
Control Subjects vs BE P Valuea |
|---|---|---|---|---|---|
| Age, y | 61.7 ± 11.1 | 65.1 ± 10.3 | <.001 | 62.9 ± 12.1 | <.001 |
| Sex | <.001 | .008 | |||
| Male | 1715 (78.6) | 1990 (87.1) | 2343 (75.5) | ||
| Female | 467 (21.4) | 294 (12.9) | 761 (24.5) | ||
| Body mass index, kg/m2 | <.001 | <.001 | |||
| Mean | 27.0 ± 4.7 | 28.4 ± 5.2 | 28.7 ± 5.1 | ||
| <25 | 786 (36.3) | 245 (24.6) | 608 (20.7) | ||
| 25–29.99 | 944 (43.5) | 455 (45.8) | 1191 (42.8) | ||
| ≥30 | 436 (20.2) | 296 (29.6) | 935 (36.5) | ||
| Missing | 16 | 1288 | 370 | ||
| Smoking status | <.001 | <.001 | |||
| Never | 888 (40.9) | 568 (25.2) | 1081 (35.2) | ||
| Ever | 1282 (59.1) | 1686 (74.8) | 1994 (64.8) | ||
| Missing | 12 | 30 | 29 | ||
| Cumulative smoking history, pack-yearsb | .43 | .001 | |||
| Mean | 32.8 ± 27.9 | 33.6 ± 26.4 | 29.4 ± 24.8 | ||
| Recurrent GERD symptoms | <.001 | <.001 | |||
| No | 1446 (80.6) | 965 (53.1) | 1058 (47.1) | ||
| Yes | 348 (19.4) | 854 (46.9) | 1186 (52.9) | ||
| Missing | 388 | 465 | 860 |
NOTE. Values are mean ± SD or n (%).
BE, Barrett’s esophagus; EA, esophageal adenocarcinoma; GERD, gastroesophageal reflux disease.
a
P value from chi-square tests for categorical variables and Student’s t test for continuous variables. Missing categories were excluded from comparison tests.
b
Among ever smokers.