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. 2018 Aug 25;7(9):240. doi: 10.3390/jcm7090240

Table 2.

Significant predictors of the failed extubation of all planned extubation patients.

Variable OR 95% CI P * OR 95% CI P **
Age (years) 1.107 1.007–1.027 0.001
APACHE II 1.046 1.027–1.066 <0.001
TISS Scale 1.036 1.017–1.055 <0.001 1.814 # 1.283–2.563 0.001
Glasgow coma scale 0.930 0.894–0.967 <0.001
Comorbidities
Chronic hemodialysis 12.970 9.483–17.740 <0.001 12.264 8.556–17.580 <0.001
Diabetes 1.507 1.110–2.045 0.008
Active cancer 0.629 0.417–0.948 0.027
Ventilator use duration (h) 1.002 1.001–1.003 <0.001
Weaning parameter
RSI 1.008 1.004–1.012 <0.001 2.003 % 1.378–2.910 <0.001
MIP 0.983 0.970–0.995 0.008
MEP 0.989 0.983–0.995 <0.001 0.610 @ 0.413–0.899 0.013
Pre-extubation data
Pulse rate 1.014 1.005–1.023 0.003 1.705 * 1.173–2.480 0.005
PaO2/FiO2 0.997 0.995–0.998 <0.001 0.529 & 0.373–0.750 <0.001
Hemoglobin 0.832 0.765–0.904 <0.001
Hematocrit (%) 0.961 0.939–0.984 0.001
BUN 1.012 1.007–1.017 <0.001

#: TISS ≥ 28.5, AUC ≈ 0.6, p < 0.001; %: RSI ≥ 49.95, AUC ≈ 0.6, p < 0.001; @: MEP < 39 cm H2O, AUC ≈ 0.6, p < 0.001; Pulse rate ≥ 102.5 /min, AUC ≈ 0.6, p = 0.026; &: PaO2/FiO2 ≤ 323.25, AUC ≈ 0.6, p < 0.001; * Value for univariate analysis; ** Value for multivariate analysis;