Table 1.
VCV 1 | FLEX | VCV 2 | |
---|---|---|---|
Healthy lung | |||
Compliance (ml·cm H2O− 1) | 53 ± 6 | 51 ± 5 | 52 ± 5 |
FlowPeak exp (ml s− 1) | − 669 ± 70 | − 261 ± 12* | − 679 ± 64* |
PEEP (cm H2O) | 8 | 8 | 8 |
Pplat (cm H2O) | 16 ± 1 | 17 ± 1 | 16 ± 1 |
Pmean (cm H2O) | 12.3 ± 0.5 | 13.7 ± 0.5* | 12.4 ± 0.4 |
VT (ml) | 419 ± 0.1 | 418 ± 0.2 | 418 ± 0.1 |
Zero flow time (s) | 1.3 ± 0.1 | 0.5 ± 0.1* | 1.3 ± 0.1 |
Injured lung | |||
Compliance (ml·cm H2O−1) | 17 ± 3 | 16 ± 3 | 17 ± 3 |
FlowPeak exp (ml s− 1) | − 970 ± 162 | − 303 ± 11* | − 968 ± 161 |
PEEP (cm H2O) | 12 ± 2 | 12 ± 2 | 12 ± 2 |
Pplat (cm H2O) | 37 ± 3 | 39 ± 2 | 36 ± 3 |
Pmean (cm H2O) | 24.6 ± 1.6 | 28 ± 3ǂ | 24.2 ± 1.7 |
VT (ml) | 418 ± 0.2 | 418 ± 0.3 | 418 ± 0.2 |
Zero flow time (s) | 1.4 ± 0.3 | 0.7 ± 0.1* | 1.4 ± 0.3 |
Data are given as mean SD
FLEX flow-controlled expiration, FlowPeak exp maximum expiratory flow, PEEP positive end-expiratory pressure, Pmean mean tracheal pressure, Pplat plateau pressure, VCV volume-controlled ventilation VT tidal volume
*Statistically significant