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. 2018 Sep 29;18:161. doi: 10.1186/s12903-018-0623-2

Table 3.

Risk of intrauterine growth restriction (IUGR) in relation to timing of dental treatment (n = 32,168)

Treatment Period of treatment Number with claims IUGR
n (%)
Adjusted odds ratio (95% confidence interval)
Overall Primiparous women Multiparous women
Periodontal Pre-gestation 428 22 (5.1%) 0.7 (0.4, 1.1) 0.5 (0.2, 1.1) 0.9 (0.5, 1.5)
Gestation 540 40 (7.4%) 1.2 (0.8, 1.7) 1.4 (0.8, 2.4) 1.1 (0.7, 1.7)
Post-birth 2088 192 (9.2%) 1.5 (1.2, 1.8) 1.3 (1.0, 1.8) 1.6 (1.3, 1.9)
Prophylaxis Pre-gestation 3387 220 (6.5%) 1.0 (0.8, 1.3) 1.0 (0.7, 1.6) 1.0 (0.7, 1.4)
Gestation 7043 409 (5.8%) 1.0 (0.8, 1.2) 1.1 (0.8, 1.6) 0.9 (0.7, 1.2)
Post-birth 11,743 743 (6.3%) 1.0 (0.8, 1.2) 0.9 (0.7, 1.2) 1.0 (0.9, 1.3)
Any dental Pre-gestation 4655 306 (6.6%) 1.2 (0.9, 1.5) 1.0 (0.7, 1.5) 1.2 (0.9, 1.7)
Gestation 8986 535 (6.0%) 0.9 (0.7, 1.1) 0.8 (0.6, 1.2) 0.9 (0.7, 1.2)
Post-birth 14,969 986 (6.6%) 1.1 (0.9, 1.3) 1.2 (0.9, 1.6) 1.1 (0.9, 1.3)

Odds ratios were adjusted for the confounding effects of maternal age, maternal age-square, household income, proportions of African-American and Hispanic ethnicities, and complications of pregnancy. An individual subject may have had a claim in more than one time period, and/or may have received more than one type of treatment in a given time period; the regression models adjust for these instances of multiple treatment exposures