Skip to main content
. 2018 Sep 25;11:6217–6226. doi: 10.2147/OTT.S177325

Figure 2.

Figure 2

Inhibition of endogenous miR-671-3p inhibits cell proliferation and migration in vitro.

Notes: (A) Expression of miR-671-3p in glioma cells transfected with miR-671-3p inhibitor or its negative control (P=0.0004 for T98G; P=0.0019 for LN229). (B) Effect of miR-671-3p inhibitor on glioma cell proliferation by CCK-8 assay. (C) Effect of miR-671-3p knockdown on T98G and LN229 cell migration by Boyden chamber (P=0.0013 for T98G; P<0.0001 for LN229). (D) Effect of miR-671-3p inhibitor on T98G and LN229 cell apoptosis by flow cytometry (P=0.0077 for T98G; P=0.0011 for LN229). B1–B4 represent dead cells, late apoptosis cells, early apoptosis cells and alive cells, respectively. Error bars represent mean ± SEM. *P<0.05, **P<0.01, ***P<0.001.

Abbreviations: CCK-8, Cell Counting Kit-8; FITC, fluorescein isothiocyanate; SEM, standard error of the mean; NC, negative control.