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. 2018 Sep 25;10:3881–3890. doi: 10.2147/CMAR.S174778

Figure 5.

Figure 5

miR-145-5p overexpression or p70S6K1 silencing effectively reverses circZNF609-induced promotion of breast cancer progression.

Notes: (A) EdU assay of MCF7 cells cotransfected with circZNF609 vector or control vector, and miR-145-5p mimics or si-p70S6K1. Scale bar=20 µm. (B, C) Transwell and wound healing assays of MCF7 cells cotransfected with circZNF609 vector or control vector, and miR-145-5p mimics or si-p70S6K1. Scale bar=20 µm. The corresponding statistical plots were exhibited in right panel. Data were represented as mean±SD of at least three independent experiments. * vs control vector group, # vs circZNF609 vector group. **P<0.01, ##P<0.01.

Abbreviation: EdU, ethynyldeoxyuridine.