Table 1.
Characteristics of the ibuprofen film-coated tablets marketed in 2011
| Code | Sales (%) | Batch | Expiration date | Weighta (mg) | Hardnessb (N) | Disc (min) | Q5d (%) | MAe (years) | Other generics |
|---|---|---|---|---|---|---|---|---|---|
| A | 11.75 | 04341PC | 03/2014 | 792.3 (5.7) | 130.4 (120.2–145.4) | 5.0 | 61.8 (8.7) | ||
| 05501PC | 04/2014 | 794.3 (5.5) | 107.8 (94.4–125.3) | 4.2 | 72.9 (9.2) | ||||
| 08818PC | 07/2014 | 788.8 (6.2) | 134.2 (119.2–139.7) | 5.3 | 73.7 (5.7) | ||||
| 08859PC | 07/2014 | 790.8 (3.8) | 115.7 (106.1–125.6) | 4.4 | 71.9 (10.0) | ||||
| 08861PC | 08/2014 | 788.0 (6.4) | 128.4 (116.5–136.7) | 5.4 | 72.2 (21.2) | ||||
| 08871PC | 08/2014 | 794.3 (10.1) | 131.0 (124.3–140.0) | 6.0 | 73.2 (14.1) | ||||
| 09891PC | 08/2014 | 793.8 (6.9) | 121.8 (114.9–127.3) | 5.0 | 84.9 (6.4) | ||||
| 09892PC | 08/2014 | 793.7 (6.3) | 135.9 (127.3–141.7) | 5.0 | 63.0 (19.8) | ||||
| 09996PC | 08/2014 | 788.5 (4.6) | 104.2 (92.4–111.2) | 5.0 | 70.7 (9.0) | ||||
| 10044PC | 09/2014 | 793.7 (10.2) | 107.3 (92.0–128.0) | 6.0 | 81.0 (6.5) | ||||
| B | 24.28 | 3E091 | 11/2014 | 969.7 (7.8) | 162.4 (144.4–182.4) | 3.1 | 72.2 (8.1) | 11 | 79 |
| 3E099 | 12/2014 | 967.8 (11.6) | 162.4 (148.4–172.0) | 3.1 | 60.0 (3.0) | ||||
| C | 15.54 | JA48211 | 12/2013 | 839.5 (3.9) | 185.3 (178.0–192.4) | 3.4 | 42.7 (11.0) | 3 | 100 |
| D | 9.19 | E071 | 06/2016 | 801 (3.9) | 200.6 (190.1–205.5) | 7.2 | 13.7 (63.5) | 6 | 125 |
| E | 9.16 | 1006922 | 03/2015 | 785.2 (5.5) | 178.3 (167.3–191.4) | 5.3 | 40.1 (16.9) | 1 | 56 |
| F | 7.35 | E128 | 10/2013 | 1,131.7 (11.7) | 138.3 (116.2–161.5) | 3.1 | 66.8 (8.3) | 8 | 119 |
| G | 5.81 | E075 | 07/2013 | 799.5 (4.8) | 197.9 (190.1–205.5) | 10.7 | 15.7 (58.1) | 5 | 94 |
| H | 4.57 | E160 | 10/2013 | 1,101.6 (13.8) | 186.9 (177.0–202.8) | 11.1 | 29.8 (10.6) | 8 | 91 |
| I | 3.08 | H303 | 06/2015 | 1,117.9 (10.1) | 156.1 (140.7–163.9) | 7.2 | 34.1 (4.1) | 6 | 84 |
| J | 2.61 | G547A | 11/2014 | 1,115.8 (7.8) | 201.4 (190.4–204.5) | 12.5 | 25.6 (16.9) | 8 | 59 |
| K | 2.38 | DK2891 | 04/2015 | 773.1 (1.5) | 143.3 (136.7–147.4) | 4.0 | 70.5 (13.5) | 7 | 66 |
| L | 1.28 | 11158 | 12/2012 | 791.0 (3.9) | 140.1 (132.7–146.8) | 6.2 | 68.2 (4.8) | 7 | 43 |
Notes:
a
Values in parenthesis are SD.
b
Mean value (minimum and maximum forces).
c
Disintegration time.
d
Values in parenthesis are the coefficients of variation.
e
Marketing age; time in years after approval.