Table 2.
Stable dose of Oxycodone DETERx at the end of the Open-label Titration Phase
| Stable dose of Oxycodone DETERxa | Subjects successfully titrated to a stable dose (N=44) n (%) |
Subjects unsuccessfully titrated to a stable dose (N=66) n (%) |
Overall (N=110) n (%) |
|---|---|---|---|
| 20 mg/day | 0 | 11 (16.7) | 11 (10.0) |
| 40 mg/day | 7 (15.9) | 10 (15.2) | 17 (15.5) |
| 60 mg/day | 6 (13.6) | 13 (19.7) | 19 (17.3) |
| 80 mg/day | 6 (13.6) | 11 (16.7) | 17 (15.5) |
| 120 mg/day | 10 (22.7) | 6 (9.1) | 16 (14.5) |
| 160 mg/day | 15 (34.1) | 15 (22.7) | 30 (27.3) |
Notes:
a
The stable dose subjects were titrated to during the Open-label Titration Phase (ie, the dose the subject entered the Double-blind Treatment Phase on) or the dose a subject was on at the time of study discontinuation (ie, withdrawal from the Open-label Titration Phase).