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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: J Struct Biol. 2018 Sep 4;204(2):283–290. doi: 10.1016/j.jsb.2018.09.002

Figure 2. Particle Picking.

Figure 2.

A. Workflow of CNN based particle picking. Top: examples of background, good and bad particle references. Bottom: Input test micrograph and output of the trained CNNs. B. A comparison of template matching to the CNN picker. Left: Template matching based particle picking, using 24 class averages as references. Right: Results of CNN based particle picking, with 20 manually selected raw references of each type (good, background and bad). C. Left: Precision-recall curves of CNN1 on a test set, with the threshold of CNN2 fixed at −5. Right: Precision- recall curves of CNN2 with the threshold of CNN1 fixed at 0.2