Table 4:
Biological Matrix | QC | Nominal Concentration (ng/mL) | Extraction Recovery | *Matrix Effect |
---|---|---|---|---|
Plasma | LQC | 2.5 | 96.8 ± 7.88 | 3.9 ± 2.23 |
MQC | 400 | 99.0 ± 1.54 | 7.5 ± 2.29 | |
HQC | 800 | 96.3 ± 3.85 | 3.6 ± 1.88 | |
Urine | LQC | 2.5 | 97.0 ± 5.39 | 6.4 ± 3.79 |
MQC | 400 | 96.6 ± 2.48 | 8.2 ± 2.76 | |
HQC | 800 | 96.6 ± 1.59 | 2.5 ± 1.28 |
Matrix effect is considered significant if matrix factor is > °15%