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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Chem Biol Drug Des. 2018 Jun 19;92(4):1736–1742. doi: 10.1111/cbdd.13341

Table 2.

IC50 values (μM) or % inhibition at 250 μM for ribavirin analogs against AGNH, GACNH, and UNH.

Compound AGNH GACNH UNH
Acadesine NMa 70% 51%
Mizoribine NM NM NM
Ribavirin 83% 8.6 ± 4.4 58%
Viramidine 0.12 ± 0.03 1.1 ± 0.6 55%
a

Not measurable (percent inhibition < 10%).