Table 2.
PNPLA3 single nucleotide polymorphisms associated with serum lipidomics of nonalcoholic fatty liver disease patients
| SNPs |
Number of SNP-associated serum lipids |
|||||||||
| CE | FFA | LPC | LPCO | LPE | PC | PCO | PE | PEO | TAG | |
| rs139051 (A/A: A/G + G/G ) | 1 | 1 | 5 | 2 | 1 | 0 | 0 | 1 | 1 | 0 |
| rs738408 (T/T: C/T + C/C) | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| rs738409 (G/G: C/G + C/C) | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| rs2072906 (G/G: A/G + A/A) | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| rs2294918 (G/G: A/A + A/G) | 0 | 0 | 3 | 3 | 1 | 1 | 0 | 9 | 0 | 5 |
| rs2294919 (C/C: C/T + T/T) | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| rs4823173 (A/A: A/G + G/G) | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CE: Cholesteryl ester; FFA: Free fatty acid; LPC: Lysophosphatidylcholine; LPCO: Lysophosphatidylcholine plasmalogen; LPE: Lysophosphatdylethanolamine; NAFLD: Nonalcoholic fatty liver disease; PC: Phosphatidylcholine; PCO: Choline plasmalogen; PE: Phosphatidylethanolamine; PEO: Ethanolamine plasmalogen; PNPLA3: Patatin-like phospholipase domain containing 3; SNP: Single nucleotide polymorphisms; TAG: Triacylglycerol.