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. 2018 Sep 26;6(10):355–364. doi: 10.12998/wjcc.v6.i10.355

Table 4.

Phospholipid metabolites correlated with pathological characteristics of nonalcoholic fatty liver disease

Phospholipid metabolites Steatosis
Lobular inflammation
Ballooning
Fibrosis
rho P value rho P value rho P value rho P value
LPC 17:0 0.149 0.399 -0.525 0.001a 0.093 0.599 0.095 0.592
LPC 18:0 0.024 0.892 -0.478 0.004a 0.136 0.442 0.089 0.618
LPC 20:0 -0.071 0.692 -0.585 0.000a 0.010 0.956 0.082 0.645
LPC 20:1 -0.061 0.734 -0.489 0.003a -0.165 0.352 -0.072 0.686
LPC 20:2 0.092 0.604 -0.453 0.007a 0.145 0.415 0.042 0.812
LPC O-16:0 0.297 0.088 -0.296 0.089 0.025 0.886 0.146 0.410
LPC O-16:1 0.070 0.695 -0.425 0.012a 0.028 0.874 0.027 0.881
LPC O-18:1 -0.114 0.521 -0.407 0.017a -0.018 0.921 0.107 0.546
LPE 20:4 -0.079 0.658 0.107 0.547 0.071 0.690 -0.071 0.692
LPE 22:6 -0.274 0.117 0.054 0.764 0.125 0.481 0.173 0.327
PC 32:1 0.020 0.913 0.086 0.630 0.107 0.547 -0.069 0.699
PE 34:0 -0.012 0.946 0.193 0.275 -0.173 0.327 -0.146 0.410
PE 34:2 -0.054 0.762 -0.025 0.888 -0.043 0.809 -0.153 0.388
PE 36:2 -0.050 0.777 -0.079 0.659 -0.118 0.506 -0.257 0.143
PE 36:4 -0.091 0.608 0.150 0.398 0.121 0.495 -0.052 0.770
PE 38:4 -0.112 0.529 0.214 0.224 0.110 0.537 -0.065 0.716
PE 38:5 -0.234 0.182 0.178 0.313 -0.026 0.885 -0.096 0.587
PE 38:6 -0.151 0.393 0.096 0.588 0.176 0.320 0.105 0.554
PE 40:5 -0.013 0.944 0.132 0.457 0.049 0.783 -0.194 0.273
PE 40:6 -0.192 0.277 0.132 0.457 0.150 0.397 0.067 0.705
PE O-36:5 0.021 0.905 0.178 0.313 -0.205 0.245 -0.131 0.461

LPC: Lysophosphatidylcholine; LPCO: Lysophosphatidylcholine plasmalogen; LPE: Lysophosphatdylethanolamine; NAFLD: Nonalcoholic fatty liver disease; PC: Phosphatidylcholine; PCO: Choline plasmalogen; PE: Phosphatidylethanolamine; PEO: Ethanolamine plasmalogen; rho: Spearman's rank correlation coefficient. aP < 0.05.