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. 2018 Sep 10;19(9):2683. doi: 10.3390/ijms19092683

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The effects of HM-3 and HM-3-Fc on the expression of TNF-α by U937 macrophages. Cells without LPS induction were used as a normal control. The other cells were inducted with LPS and the cells without drug treatment were used as a negative control. The other cells were incubated with HM-3 or HM-3-Fc at indicated concentrations, with 50 μg/mL Adalimumab as a positive control drug. Results were presented as mean ± SD (n = 3). ### p < 0.001 vs. Blank Control. * p < 0.05, ** p < 0.01 and *** p < 0.001 vs. Negative Control.